Tissue culture studies on a suspected lysosomal storage disease in Abyssinian cats.
نویسنده
چکیده
Cell cultures prepared from the spleen and mesenteric lymph nodes of affected kittens were subjected to histochemical and ultrastructural studies. Macrophages in the cultures contained lipid in the cytoplasm and the ultrastructural studies revealed lysosomes containing lamellae similar in appearance to phospholipids.
منابع مشابه
Progressive retinal atrophy in the Abyssinian cat.
Eight cases of hereditary progressive retinal atrophy in Abyssinian cats in Denmark are reported. Pedigree studies indicate direct lineage to affected cats of the same breed in Sweden. The disease is bilateral, progressive, and of the generalized type, and ultimately leads to blindness.
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OBJECTIVE To characterize hereditary retinal degeneration in the Abyssinian cat (rdAc) in a recently established closed colony segregating for the rdAc mutation, and evaluate possible differences in the age of onset and progression of disease phenotype since the initial description of rdAc 25 years ago. The sample size of an earlier study was increased in order to determine the allele frequency...
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عنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 47 2 شماره
صفحات -
تاریخ انتشار 1980